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10mg/1ml Chlorpheniramine Injection / Chlorphenamine Maleate Injection

Categories Small Volume Parenteral
MOQ: 500, 000 amps
Payment Terms: L/C, T/T
Delivery Time: 45days
Packaging Details: 10 x 10amps/box
Brand Name: Newlystar
Place of Origin: China
Model Number: 10mg/1ml
Certification: GMP
Price: Negotiation
Supply Ability: one million amps per day
Product: Chlorpheniramine Injection
Specification: 10mg/1ml
Standard: BP, USP
Packing: 10 x 10amps/box
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    10mg/1ml Chlorpheniramine Injection / Chlorphenamine Maleate Injection

    10mg/1ml Chlorpheniramine Injection / Chlorphenamine Maleate Injection


    Product : Chlorpheniramine Injection

    Specification : 10mg/1ml

    Standard : BP, USP

    Packing : 10 x 10amps/box


    Description :

    Chlorpheniramine is a histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine.


    Indication

    For the treatment of rhinitis, urticaria, allergy, common cold, asthma and hay fever.


    Pharmacodynamics

    In allergic reactions an allergen interacts with and cross-links surface IgE antibodies on mast cells and basophils. Once the mast cell-antibody-antigen complex is formed, a complex series of events occurs that eventually leads to cell-degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil. Once released, histamine can react with local or widespread tissues through histamine receptors. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, hypotension, flushing, headache, tachycardia, and bronchoconstriction. Histamine also increases vascular permeability and potentiates pain. Chlorpheniramine, is a histamine H1 antagonist (or more correctly, an inverse histamine agonist) of the alkylamine class. It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies.


    Mechanism of action

    Chlorpheniramine binds to the histamine H1 receptor. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine.

    Product Tags:

    Small Volume Injection

      
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